منابع مشابه
Hepatic Intracellular Osmiophilic Droplets
Lipid solvent extraction of aldehyde-fixed hepatic tissue of rats caused disappearance of all intravascular and hepatocellular osmiophilic droplets normally present, thus indicating their lipid content. Intramitochondrial dense granules and osmiophilic droplets in lysosomes also disappeared after this treatment. Lipid solvents extracted 43.8 to 92.6% of the radioactivity from aldehyde-fixed rat...
متن کاملIntracellular Lipid Droplets: From Structure to Function
Lipid droplets (LDs) are unique intracellular organelles that are mainly constituted by neutral lipids (triglycerides, sterol esters). As such they serve as the main site of energy storage in the cell and they are akin to oil emulsions in water. To prevent the direct exposure of the hydrophobic neutral lipids to the aqueous environment of the cytosol, LDs are surrounded by a monolayer of phosph...
متن کاملThe Obligate Intracellular Pathogen Chlamydia trachomatis Targets Host Lipid Droplets
Lipid droplets (LDs) are ubiquitous but poorly understood neutral-lipid-rich eukaryotic organelles that may participate in functions as diverse as lipid homeostasis, membrane traffic, and signaling . We report that infection with the obligate intracellular pathogen Chlamydia trachomatis, the causative agent of trachoma and many sexually transmitted diseases , leads to the accumulation of neutra...
متن کاملFat on the move: intracellular motion of lipid droplets.
Lipid droplets are intracellular organelles that play central roles in lipid metabolism. In many cells, lipid droplets undergo active motion, typically along microtubules. This motion has been proposed to aid growth and breakdown of droplets, to allow net transfer of nutrients from sites of synthesis to sites of need and to deliver proteins and lipophilic signals. This review summarizes the cur...
متن کاملA long wavelength hydrophobic probe for intracellular lipid droplets.
A highly stable, long wavelength polarity sensitive probe, 8-nitrophenyl-3,5-dipiperidine-4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (NPBDP), was developed for living cell imaging of intracellular lipid droplets by fluorescence microscopy.
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 1966
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.31.2.301